1 Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran

2 Analytical Research Laboratory, Department of Chemistry, University of Sistan and Baluchestan, Zahedan, Iran

3 English Department, Zahedan University of Medical Sciences, Zahedan, Iran

4 Department of Environmental Health, Graduate School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


The current study aimed to examine the overall feasibility of the use of copper oxide nanoparticles (CuO-NPs) as a catalyst in ozonation process for the removal of benzene from aqueous solutions under experimental conditions. This experimental study was conducted on a laboratory scale reactor in a semi-batch mode. The effect of critical operating parameters such factors as pH, concentration of benzene, reaction time and nano-catalyst dose on the removal of benzene was investigated. The samples included with benzene concentrations (10-200 mg/L), pH (3-13), catalyst dose (0.1-0.5 mg), and ozonation time (5-50 min). Findings indicated that the removal of benzene depended on various utilization parameters. The highest efficiency was achieved at reaction time of 50 min, pH of 12, initial benzene concentration of 10 mg/L and catalyst dose of 0.5 g. Among the studied factors, the maximum and the minimum contributions were made by the dose of nanoparticles (83%) and the reaction time (~73%). The software predicted that use of 0.13 g of the catalyst at pH of 12 and ozonation time of 5 min would lead to a removal efficiency of 68.4%. The catalytic ozonation process was able to remove benzene, and addition of CuO-NPs as a catalyst together with the ozonation process increased the benzene removal efficiency. The values of R2 = 0.9972, adjusted R2= 0.9946, and predicted R2 =0.9893 indicated that the model was acceptably predicted by the software and fitted the data obtained in the experiments.

Graphical Abstract

Optimization of the catalytic ozonation process using copper oxide nanoparticles for the removal of benzene from aqueous solutions


  • Removal of benzene was dependent on various utilization parameters
  • The highest efficiency was achieved at reaction time of 50 min, pH of 12, initial benzene concentration of 10 mg/L and catalyst dose of 0.5 g
  • The maximum contribution was made by the quantity of the nanoparticles (83%) and the minimum by the reaction time (~73%). 


Main Subjects

Abdel-Ghani, N. T.; Rawash, E.S.A.; El-Chaghaby, G.A., (2016). Equilibrium and kinetic study for the adsorption of p-nitrophenol from wastewater using olive cake based activated carbon. Global J. Environ. Sci. Manage., 2(1): 11-18 (8 pages).

Absalan, G.; Asadi, M.; Kamran, S.; Sheikhian, L.; Goltz, D.M., (2011). Removal of reactive red-120 and 4-(2-pyridylazo) resorcinol from aqueous samples by Fe3O4 magnetic nanoparticles using ionic liquid as modifier. J. Hazard. Mater., 192(2): 476-484 (9 pages).

Bazrafshan, E.; Biglari, H.; Mahvi, A.H., (2012a). Humic acid removal from aqueous environments by electrocoagulation process using iron electrodes. J. Chem., 9(4): 2453-2461 (9 pages).

Bazrafshan, E.; Biglari, H.; Mahvi, A.H., (2012b). Phenol removal by electrocoagulation process from aqueous solutions. Fresen. Environ. Bull., 21(2): 364-371 (8 pages).

Bazrafshan, E.; Mostafapour, FK.; Farzadkia, M.; Ownagh, KA.; Mahvi, AH., (2012c). Slaughterhouse wastewater treatment by combined chemical coagulation and electrocoagulation process. PLoS One 7(6), e40108 (8 pages).

Bina, B.; Pourzamani, H.; Rashidi, A.; Amin, M.M., (2012). Ethylbenzene removal by carbon nanotubes from aqueous solution. J. Environ. Public Health., 2012 (8 pages).

Choi, H.; Al-abed, S.R.; Dionysiou, D.D.; Stathatos, E.; Lianos, P., (2010). TiO2-based advanced oxidation nanotechnologies for water purification and reuse. Sustain. Sci. Eng., 2: 229-254 (26 pages).

De Mello, J.M.M.; De Lima Brandao, H.; De Souza, A.A.U.; Da Silva, A.; Ulson, S.M.d.A.G., (2010). Biodegradation of BTEX compounds in a biofilm reactor-modeling and simulation. J. Petrol. Sci. Eng.., 70(1): 131-139 (9 pages).

Erol, F.; Özbelge, T.A., (2008). Catalytic ozonation with non-polar bonded alumina phases for treatment of aqueous dye solutions in a semi-batch reactor. Chem. Eng. J., 139(2): 272-283 (12 pages).

Fakhri, A., (2015). Investigation of mercury (II) adsorption from aqueous solution onto copper oxide nanoparticles: optimization using response surface methodology. Process Saf. Environ. Prot., 93: 1-8 (8 pages).

Farzadkia, M.; Bazrafshan, E.; Esrafili, A.; Yang, J.K.; Shirzad-Siboni, M., (2015). Photocatalytic degradation of Metronidazole with illuminated TiO2 nanoparticles. J. Environ. Health. Sci. Eng., 13(35) (8 pages).

Fink, L.; Dror, I.; Berkowitz, B., (2012). Enrofloxacin oxidative degradation facilitated by metal oxide nanoparticles. Chemosphere, 86(2): 144-149 (6 pages).

Gupta, V.K.; Suhas; Tyagi, I.; Agarwal, S.; Singh, R.; Chaudhary, M.; Harit, A.; Kushwaha, S., (2016). Column operation studies for the removal of dyes and phenols using a low cost adsorbent. Global J. Environ. Sci. Manage., 2 (1): 1-10 (10 pages).

Han, W.K.; Choi, J.W.; Hwang, G. H.; Hong, S. J.; Lee, J. S.; Kang, S.G., (2006). Fabrication of Cu nano particles by direct electrochemical reduction from CuO nano particles. Appl. Surf. Sci., 252(8): 2832-2838 (7 pages).

Jaspal, D.; Malhotra, S.; Malviya, A., (2012). Column studies for the adsorption of brilliant green, fast green FCF and phenol red dyes on de-oiled soya and bottom ash. Asian J. Chem., 24(11): 5082-5086 (5 pages).

Ji, F.; Li, C.; Deng, L., (2011). Performance of CuO/Oxone system: Heterogeneous catalytic oxidation of phenol at ambient conditions. Chem. Eng. J., 178: 239-243 (5 pages).

Kakavandi, B.; Kalantary, R.R.; Farzadkia, M.; Mahvi, A.H.; Esrafili, A.; Azari, A.; Yari, A.R.; Javid, A.B., (2014). Enhanced chromium (VI) removal using activated carbon modified by zero valent iron and silver bimetallic nanoparticles. J. Environ. Health Sci. Eng., 12(1) (115 pages).

Khajeh, M., (2011). Response surface modelling of lead pre-concentration from food samples by miniaturised homogenous liquid–liquid solvent extraction: Box–Behnken design. Food. Chem., 129(4): 1832-1838 (7 pages).

Khamparia, S.; Jaspal, D., (2016a). Adsorptive removal of Direct Red 81 dye from aqueous solution onto Argemone mexicana. Sustainable Environ. Res., 26(3): 117-123 (7 pages).

Khamparia, S.; Jaspal, D., (2016b). Investigation of adsorption of Rhodamine B onto a natural adsorbent Argemone mexicana. J. Environ. Manage., 183: 786-793 (8 pages).

Khamparia, S.; Jaspal, D.K., (2016c). Evaluation of decoloration potential of Xanthium Strumarium seed hull for adsorption of Direct red 81 in aqueous solution. Environ. Dev. Sustain., 1-19 (19 pages).

Khamparia, S.; Jaspal, D., (2017a). Study of decolorisation of binary dye mixture by response surface methodology. J. Environ. Manage., 201: 316-326 (11 pages).

Khamparia, S.; Jaspal, D.K., (2017b). Adsorption in combination with ozonation for the treatment of textile waste water: a critical review. Front. Environ. Sci. Eng., 11(1): (8 pages).

Khan, M.H.; Jung, J.Y., (2008). Ozonation catalyzed by homogeneous and heterogeneous catalysts for degradation of DEHP in aqueous phase. Chemosphere 72(4): 690-696 (7 pages).

Kruithof, J.C.; Kamp, P.C.; Martijn, B.J., (2007). UV/H2O2 treatment: A practical solution for organic contaminant control and primary disinfection. Ozone: Sci. Eng., 29(4): 273-280 (8 pages).

Kurniawan, T.A.; Lo, W.H.; Chan, G.Y., (2006). Degradation of recalcitrant compounds from stabilized landfill leachate using a combination of ozone-GAC adsorption treatment. J. Hazard. Mater., 137(1): 443-455 (13 pages).

Mahamuni, N.N.; Pandit, A.B., (2006). Effect of additives on ultrasonic degradation of phenol. Ultrasonics Sonochem., 13(2): 165-174 (10 pages).

Mahvi, A.; Maleki, A.; Rezaee, R.; Safari, M., (2009). Reduction of humic substances in water by application of ultrasound waves and ultraviolet irradiation. J. Environ. Health Sci. Eng., 6(4): 233-240 (8 pages).

Martinson, C.A.; Reddy, K., (2009). Adsorption of arsenic (III) and arsenic (V) by cupric oxide nanoparticles. J. Colloid Interface Sci., 336(2): 406-411 (6 pages).

Mittal, A.; Kaur, D.; Mittal, J., (2009). Batch and bulk removal of a triarylmethane dye, Fast Green FCF, from wastewater by adsorption over waste materials. J. Hazard. Mater., 163(2): 568-577 (10 pages).

Mohammadi, L.; Bazrafshan, E.; Noroozifar, M.; Ansari-Moghaddam, A., (2016). Application of heterogeneous catalytic ozonation process with magnesium oxide nanoparticles for Toluene degradation in aqueous environments. Health Scope., 5(4): :e40439 (11 pages).

Mortazavi, S.; Asgari, G.; Hashemian, S.; Moussavi, G., (2010). Degradation of humic acids through heterogeneous catalytic ozonation with bone charcoal. React. Kinet., Mech. Catal., 100(2): 471-485 (15 pages).

Moussavi, G.; Khosravi, R.; Farzadkia, M., (2011). Removal of petroleum hydrocarbons from contaminated groundwater using an electrocoagulation process: Batch and continuous experiments. Desalination 278(1): 288-294 (7 pages).

Moussavi, G.; Alizadeh, R., (2010). The integration of ozonation catalyzed with MgO nanocrystals and the biodegradation for the removal of phenol from saline wastewater. Appl. Catal. B., 97(1): 160-167 (8 pages).

Moussavi, G.; Khavanin, A.; Alizadeh, R., (2009a). The investigation of catalytic ozonation and integrated catalytic ozonation/biological processes for the removal of phenol from saline wastewaters. J. Hazard. Mater., 171(1): 175-181 (7 pages).

Moussavi, G.; Mahmoudi, M., (2009b). Degradation and biodegradability improvement of the reactive red 198 azo dye using catalytic ozonation with MgO nanocrystals. Chem. Eng. J. 152(1): 1-7 (7 pages).

Moussavi, G.; Mahmoudi, M., (2009c). Removal of azo and anthraquinone reactive dyes from industrial wastewaters using MgO nanoparticles. J. Hazard. Mater., 168(2): 806-812 (7 pages).

Ramachandran, K.; Suganya, T.; Gandhi, N.N.; Renganathan, S., (2013). Recent developments for biodiesel production by ultrasonic assist transesterification using different heterogeneous catalyst: a review. Renewable Sustainable Energy Rev., 22: (410-418) (9 pages).

Rosenfeldt, E.J.; Linden, K.G.; Canonica, S.; Von Gunten, U., (2006). Comparison of the efficiency of OH radical formation during ozonation and the advanced oxidation processes O3/H2O2 and UV/H2O2. Water Res. 40(20): 3695-3704 (10 pages).

Sánchez-Polo, M.; Von Gunten, U.; Rivera-Utrilla, J., (2005). Efficiency of activated carbon to transform ozone into OH radicals: influence of operational parameters. Water Res., 39(14): 3189-3198 (10 pages).

Stepnowski, P.; Siedlecka, E.; Behrend, P.; Jastorff, B., (2002). Enhanced photo-degradation of contaminants in petroleum refinery wastewater. Water Res., 36(9): 2167-2172 (6 pages).

Sui, M.; Xing, S.; Sheng, L.; Huang, S.; Guo, H., (2012). Heterogeneous catalytic ozonation of ciprofloxacin in water with carbon nanotube supported manganese oxides as catalyst. J. Hazard. Mater. 227: 227-236 (10 pages).

Turkay, O.; Inan, H.; Dimoglo, A., (2014). Experimental and theoretical investigations of CuO-catalyzed ozonation of humic acid. Sep. Purif. Technol., 134: 110-116 (7 pages).

Umar, M.; Roddick, F.; Fan, L.; Aziz, H.A., (2013). Application of ozone for the removal of bisphenol A from water and wastewater–a review. Chemosphere 90(8): 2197-2207 (11 pages).

Valdés, H.; Farfán, V.J.; Manoli, J.A.; Zaror, C.A., (2009). Catalytic ozone aqueous decomposition promoted by natural zeolite and volcanic sand. J. Hazard. Mater. 165(1): 915-922 (8 pages).

Valdes, H.; Murillo, F.; Manoli, J.; Zaror, C., (2008). Heterogeneous catalytic ozonation of benzothiazole aqueous solution promoted by volcanic sand. J. Hazard. Mater. 153(3): 1036-1042 (7 pages).

Wu, J.; Zhang, H.; Oturan, N.; Wang, Y.; Chen, L.; Oturan, M.A., (2012). Application of response surface methodology to the removal of the antibiotic tetracycline by electrochemical process using carbon-felt cathode and DSA (Ti/RuO2–IrO2) anode. Chemosphere 87(6): 614-620 (7 pages).

Zazouli, M.A.; Mahvi, A.H.; Dobaradaran, S.; Barafrashtehpour, M.; Mahdavi, Y.; Balarak, D., (2014). Adsorption of fluoride from aqueous solution by modified Azolla filiculoides. Fluoride. 2014; 47 (4): 349-358 (10 pages).

Zeng, Y.F.; Liu, Z.L.; Qin, Z.Z., (2009). Decolorization of molasses fermentation wastewater by SnO2-catalyzed ozonation. J. Hazard. Mater. 162(2): 682-687 (6 pages). 

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